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Title   원발성 간세포암의 Lipiodol - Cisplatin 화학색전요법의 치료효과 ( Therapeutic Effect of Transarterial Chemoembolization Using Cisplatin - Lipiodol Mixture in Hepatocellular Carcinoma )
Publicationinfo   1993 Jan; 025(04): 494-501.
Key_word   Hepato cellular carcinoma, Chemoembolization
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Abstract   Chemoembolization therapy, using the arterial injection of ciplatin-lipiodol mixture(Cis- platin-LP-TACE), was carried out on 31 cases of hepatocellular carcinoma(HCC) between January 1989 and December 1991, and assessment was made on the anticancer effects of this treat- ment method. For the patients receiving LP-TACE, the value of longitudinal dimension multiplied by the vertical lengths of the tumor was calculated using a computerized tomograph before and after LP-TACE to determine the rate of tumor regression. Among 28 evaluable patients, there were 2 complete response, giving a response rate of 7% and 6 partial response(21.5%). Six patients(21.5%) achieved disease stabilization and 14 cases(50%) had tumor progression. One-year survival rates for TACE group was 35%, and median survival times was 8.1 months. Toxicity was moderate and consisited of nausea, vomiting, fever and abdominal pain. In conclusion, Cisplatin-LP-TACE appears to be an effective therapy in treating patients with unresectable HCC and relatively well tolerated in most patients.
저 자   김미선(Mi Sun Kim),조기범(Gi Bum Cho),박무인(Mu In Park),우인기(In Ki Woo),이수정(Soo Jung Lee),이상욱(Sang Wook Lee),한병훈(Byung Hoon Han),박병채(Byung Chae Park),허진도(Jin Do Hur),조영덕(Young Duk Cho)